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Discovery & Innovation

Showing 131-140 of 185 posts
Feb 26, 2014

Previously, we discussed in part 1 of this series the growing significance of computational methods in drug discovery. Traditional drug discovery...

Feb 20, 2014

Most people have probably heard of Alexander Fleming’s chance encounter with a penicillin-producing fungus. What is not quite well-known is that...

Feb 18, 2014

Traditional drug discovery is expensive, inefficient, and has huge barriers to entry. Big pharmaceutical companies continue to struggle to cope...

Feb 14, 2014

A quick scan of recent advances in the scientific community will show that genomic data and new techniques in next-gen sequencing have been gaining...

Feb 13, 2014

This is the third and final post of a series (part 1 and part 2) on directed evolution. What do protein engineers actually produce using directed...

Feb 11, 2014

Three outstanding examples for fragment-based drug discovery A good example for the reliability of the fragment-based screening method is the...

Feb 6, 2014

Directed evolution is emerging as a powerful new tool to design proteins with new and interesting properties that may not have evolved naturally...

Feb 4, 2014

Illumina recently announced the $1000 solution for the sequencing of the human genome in the form of its new instrument, the HiSeqX. This system...

Jan 30, 2014

The selection and accumulation of desirable mutations – also known as natural selection – has shaped the living world. The proteins resulting from...

Jan 28, 2014

One major challenge in drug discovery is determining whether a drug is behaving as intended, binding the “right” protein, inhibiting the correct...